Osteoarthritis (OA) is an incurable degenerative and painful disease of the joints that reduces the quality of life of dogs and cats.
OA pain is a complicated process mediated by many factors, including nerve growth factor (NGF), a signaling protein that is produced by injured tissues.
Monoclonal antibodies (mAbs) are highly specific immune system molecules that can be used therapeutically to target and neutralize molecules involved in disease.
Studies have demonstrated that the anti-NGF monoclonal antibody is an effective analgesic for targeted and sustained relief from OA pain. Additionally, anti-NGF mAbs are long-acting biologic therapeutics that are safely broken down like all other proteins.
Watch the video below for more details on precisely how anti-NGF mAbs work to relieve OA pain.